About Methyl Acetoacetate
Methyl Acetoacetate
Methyl Acetoacetate is a clear and colourless liquid solution that is slightly soluble in water, but denser than water. It is produced when methyl acetate reacts with sodium methoxide. This chemical reagent acts as a raw material in the syntheses of pharmaceuticals, alpha-substituted aceto- acetic esters and cyclic compounds. It is also used in Biginelli reaction, that forms molecules such as dihydropyrimidinones. Other manufacturing processes used to produce uracil herbicides bromacil and terbacil, and organophosphorus insecticide diazinon, also use this chemical. Large quantities of Methyl Acetoacetate are supplied in drums.
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Specifications:
| Formula | C5H8O3 |
| Molecular weight | 116.12 |
| CAS RN | 105-45-3 |
| Minimum assay | 99.00% |
| Minimum stability | 2 years |
| Melting point ca. | -28 Deg C |
| Boiling point ca. | 170 Deg C |
| Density g/cm3 (20 Deg C) | 1.077 |
| EU labeling | Xi irritant |
| Packaging | drums, bulk |
| Transport information | not restricted |
Versatile Chemical IntermediateMethyl Acetoacetate is widely valued as a key building block in organic synthesis. Its high purity and reactive structure make it essential for producing pharmaceuticals, agrochemicals, dyestuffs, and flavoring compounds. The compounds adaptability and efficiency streamline chemical manufacturing processes across industries.
Safe Storage and TransportThis liquid remains stable when stored in cool, dry, well-ventilated environments, away from heat and sunlight. Despite being an irritant to eyes and skin, Methyl Acetoacetate is classified as non-hazardous for transportation under standard conditions, ensuring practical and safe handling for suppliers and processors.
Physical and Chemical PropertiesMethyl Acetoacetate features a boiling point of 172 C, flash point of 63 C, and an autoignition temperature of 496 C. It possesses a neutral pH and is partially soluble in water but readily mixes with ethanol and ether, supporting its varied uses in laboratory and industrial settings.
FAQs of Methyl Acetoacetate:
Q: How should Methyl Acetoacetate be stored for maximum shelf life?
A: Store Methyl Acetoacetate in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat to ensure stability and maintain its 12-month shelf life.
Q: What is the main application of Methyl Acetoacetate?
A: It is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, dyestuffs, and flavoring agents due to its reactive and versatile chemical structure.
Q: When is it necessary to ensure specialized handling for Methyl Acetoacetate?
A: Specialized handling is required when there is a risk of exposure to eyes and skin, as the substance is classified as an irritant. Always use appropriate personal protective equipment during handling.
Q: Where can you source Methyl Acetoacetate for industrial use?
A: It is available from chemical suppliers, exporters, and importers in India, usually provided in drums, bottles, or IBC tanks for industrial-grade applications.
Q: What process is used to manufacture Methyl Acetoacetate?
A: Methyl Acetoacetate is produced via chemical synthesis, ensuring high purity and consistent quality appropriate for a range of industrial applications.
Q: How can Methyl Acetoacetate benefit manufacturing processes?
A: Its chemical stability, high purity, and miscibility with various solvents make it advantageous as a building block in the efficient production of diverse chemical products.
Q: Is Methyl Acetoacetate considered hazardous during transport?
A: No, under standard transport conditions, Methyl Acetoacetate is classified as non-hazardous, enabling safe and straightforward shipment.